Welcome to Steve Ley’s Organic Chemistry research group webpages. Our laboratories, the Whiffen and Innovative Technology Centre are in the Department of Chemistry at the University of Cambridge. Here you’ll find details of our current research as well as a look back at some of our historical achievements in natural product synthesis and other areas of organic synthesis. Visitors from academia and industry are welcome to come and work with us and are invited to get in touch.
Hot of the Press!
Machines vs Malaria: A Flow-Based Preparation of the Drug Candidate OZ439
Modelling Mesoscale Reactors for the Production of Fine Chemicals
A Versatile Room-Temperature Route to Di- and Trisubstituted Allenes Using Flow-Generated Diazo compounds
Latest Research Articles
- A Versatile Room-Temperature Route to Di- and Trisubstituted Allenes Using Flow-Generated Diazo compounds
- Generation of Reactive Ketenes under Flow Conditions through Zinc-Mediated Dehalogenation
- Facilitating Biomimetic Syntheses of Borrerine Derived Alkaloids by Means of Flow-Chemical Methods
- Development of a Web-based Platform for Studying Lithiation Reactions in Silico
- Development of a Flow Method for the Hydroboration/Oxidation of Olefins
- Design, Synthesis and Evaluation of Tetra-substituted Pyridines as Potent 5-HT2C Receptor Agonists
- Flow Cyclopropanation Using in-situ Generated Diazo Compounds
- Flow Chemistry: Intelligent Processing of Gas-Liquid Transformations Using a Tube-in-Tube Reactor
- Organic Synthesis: March of the Machines
- Flow Chemistry Meets Advanced Functional Materials
- Chemistry in a Changing World
- Flow chemistry syntheses of natural products
“Complex synthesis remains a challenging occupation requiring an exceptional level of experimental skill, extensive knowledge of both mechanistic and molecular reactivity, and a bold, inventive, and creative spirit. It is the combination of these qualities that transforms the synthesis process from one of simple logistics to an art form.” Steve Ley.