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Welcome to Steve Ley’s Organic Chemistry research group webpages. Our laboratories, the Whiffen and Innovative Technology Centre are in the Department of Chemistry at the University of Cambridge. Here you’ll find out about our current research in flow chemistry and organic synthesis, as well as a look back at our historical achievements in natural product synthesis. Visitors from academia and industry are welcome to come and work with us and are invited to get in touch.

PAPERS IN PRESS

On the synthesis and reactivity of 2,3-dihydropyrrolo[1,2-a] quinazolin-5(1H)-ones

Continuous processing and efficient in situ reaction monitoring of a hypervalent iodine(III) mediated cyclopropanation using benchtop NMR spectroscopy

The total synthesis of the bioactive natural product plantazolicin A and its biosynthetic precursor plantazolicin B

A multicomponent approach for the preparation of homoallylic alcohols

RECENT REVIEWS

• Enabling Technologies for the Future of Chemical Synthesis
• Machine-Assisted Organic Synthesis
• Flow Chemistry: Intelligent Processing of Gas-Liquid Transformations Using a Tube-in-Tube Reactor
• Organic Synthesis: March of the Machines
• Flow Chemistry Meets Advanced Functional Materials
• Chemistry in a Changing World
• Flow Chemistry Syntheses of Natural Products

NEW STUFF

• Our Knowledge Transfer activities and a virtual tour around our Flow Laboratory.
• The Internet of Chemical Things – the IoCT which we define as the interconnection and networking of chemical machines, computing devices and all chemical services delivered through the infrastructure of the Internet is coming.
• Organic Chemistry Science Gateway – enabling researchers to rationalise and predict organic reactions using computational analysis in silico.

APRIL’S SYMPOSIUM PHOTO GALLERY

We have a huge gallery of professional photographs from Steve’s 70th Birthday symposium in April. If you would like to reproduce any images please include a photographer’s credit line (Nathan Pitt). If you would like a different size, format or resolution of any image, please contact photography@ch.cam.ac.uk.

VIDEOS

• Creator Space™ Science Symposium – Steve’s lecture at the BASF anniversary conference
• Flow Chemistry: Introducing the Innovative Technology Centre

“Complex synthesis remains a challenging occupation requiring an exceptional level of experimental skill, extensive knowledge of both mechanistic and molecular reactivity, and a bold, inventive, and creative spirit. It is the combination of these qualities that transforms the synthesis process from one of simple logistics to an art form.” Steve Ley.