Welcome to the website of Professor Steven V. Ley FRS CBE and his organic chemistry research group. Our labs (The Whiffen and the Innovative Technology Centre) are in the Department of Chemistry at the University of Cambridge.
- Flow based cerium oxide-enhanced low-level palladium Sonogashira and Heck coupling reactions by perovskite type oxide catalysts
- Machine-assisted synthesis of modulators of the histone reader BRD9 using flow methods of chemistry and frontal affinity chromatography
- Fully automated sequence-specific synthesis of α-peptides using flow chemistry
- Integration of enabling methods for the automated flow preparation of piperazine-2-carboxamide
- Mild and selective heterogeneous catalytic hydration of nitriles to amides by flowing through manganese dioxide
New Reviews: Camera enabled techniques for organic synthesis and Flow chemistry syntheses of natural products
- Conducting Appel reactions in flow using a triphenylphosphine monolith Steve gives a one-on-one tutorial about flow chemistry and demonstrates how these systems can be applied to a given reaction in practice.
- Flow chemistry: introducing the Innovative Technology Centre Steve shows you around the ITC and explains what can be achieved using automated flow methods.
“Complex synthesis remains a challenging occupation requiring an exceptional level of experimental skill, extensive knowledge of both mechanistic and molecular reactivity, and a bold, inventive, and creative spirit. It is the combination of these qualities that transforms the synthesis process from one of simple logistics to an art form.” Steve Ley
Email any comments about the website to rmm32@cam.ac.uk. We welcome academic and industry visitors to our group.