Welcome to Steve Ley’s Organic Chemistry research group webpages. Our laboratories, the Whiffen and Innovative Technology Centre are in the Department of Chemistry at the University of Cambridge. Here you’ll find details of our current research as well as a look back at some of our historical achievements in natural product synthesis and other areas of organic synthesis. Visitors from academia and industry are welcome to come and work with us and are invited to get in touch.
NEW STUFF & EARLY VIEWS
Creator Space™ Science Symposium – Steve’s lecture at the BASF anniversary conference
Organic Chemistry Science Gateway – enabling researchers to rationalise and predict organic reactions using computational analysis in silico.
- Continuous Flow Metathesis for Direct Valorization of Food Waste: An Example of Cocoa Butter Triglyceride
- A Versatile Room-Temperature Route to Di- and Trisubstituted Allenes Using Flow-Generated Diazo Compounds
- Machines vs Malaria: a Flow-based Preparation of the Drug Candidate OZ439
- Modeling Mesoscale Reactors for the Production of Fine Chemicals
- Callipeltosides A, B & C: Total Syntheses and Structural Confirmation
- Design, Synthesis and Evaluation of Semi-synthetic Triazole-containing Caffein Acid Analogues as 5-Lipoxygenase Inhibitors
- A Practical Deca-gram Scale Ring Expansion of (R)-(−)-Carvone to (R)-(+)-3-Methyl-6-isopropenyl-cyclohept-3-enone-1
- Machine-Assisted Organic Synthesis
- Flow Chemistry: Intelligent Processing of Gas-Liquid Transformations Using a Tube-in-Tube Reactor
- Organic Synthesis: March of the Machines
- Flow Chemistry Meets Advanced Functional Materials
- Chemistry in a Changing World
- Flow Chemistry Syntheses of Natural Products
“Complex synthesis remains a challenging occupation requiring an exceptional level of experimental skill, extensive knowledge of both mechanistic and molecular reactivity, and a bold, inventive, and creative spirit. It is the combination of these qualities that transforms the synthesis process from one of simple logistics to an art form.” Steve Ley.