Welcome to the website of Professor Steven V. Ley FRS CBE and his organic chemistry research group. Our labs (The Whiffen and the Innovative Technology Centre) are in the Department of Chemistry at the University of Cambridge.
- Synthesis of riboflavines, quinoxalinones and benzodiazepines through chemoselective flow based hydrogenations
- Preparation of unsymmetrical ketones from tosylhydrazones and aromatic aldehydes via formyl C-H bond insertion
- Synthesis and use of trifluoromethylated azomethine ylide precursor: ethyl 1-benzyl-trans-5-(trifluoromethyl) pyrrolidine-3-carboxylate
- Continuous flow chemistry: a discovery tool for new chemical reactivity patterns
- Accelerating spirocyclic polyketide synthesis using flow chemistry
- Flow based cerium oxide-enhanced low-level palladium Sonogashira and Heck coupling reactions by perovskite type oxide catalysts
- Machine-assisted synthesis of modulators of the histone reader BRD9 using flow methods of chemistry and frontal affinity chromatography
- Fully automated sequence-specific synthesis of α-peptides using flow chemistry
“Complex synthesis remains a challenging occupation requiring an exceptional level of experimental skill, extensive knowledge of both mechanistic and molecular reactivity, and a bold, inventive, and creative spirit. It is the combination of these qualities that transforms the synthesis process from one of simple logistics to an art form.” Steve Ley
Email any comments about the website to email@example.com. We welcome academic and industry visitors to our group.