Home
Welcome to Steve Ley’s research group webpages. Our laboratory is housed in the Yusuf Hamied Department of Chemistry at the University of Cambridge. Here you’ll find out about our current research in flow chemistry and organic synthesis, as well as a look back at our historical achievements in natural product synthesis.
Synthesis is changing in response to our modern resource conscious world. The principles of green chemistry are evolving as the interfaces and boundaries in science are less obvious and providing a new stimuli for future discovery. The invention and application of new chemical reactivity continues to be a primary driver since this opens up so many strategic opportunities for synthesis.
“Complex synthesis remains a challenging occupation requiring an exceptional level of experimental skill, extensive knowledge of both mechanistic and molecular reactivity, and a bold, inventive, and creative spirit. It is the combination of these qualities that transforms the synthesis process from one of simple logistics to an art form.” Steve Ley.
In 2018, Steve was awarded the Arthur C. Cope Award. The prize is awarded for achievement in the field of organic chemistry research, and is one of the highest honours in the field. This was the first time the prize was given to someone working in the UK and recognizes outstanding achievement in the field of organic chemistry within the five years preceding the award. The prize is sponsored by the Arthur C. Cope Fund and has been awarded since 1973 by the American Chemical Society. Arthur C. Cope, an influential organic chemist, is credited with the development of several important chemical reactions which bear his name, including the Cope elimination and the Cope rearrangement.
New Path Molecular a new company originating from our labs, now based on the Babraham Research Campus, specialises in the chemical synthesis of complex functional molecules using cutting edge techniques, methods and instrumentation. Their outputs are being used to validate biological processes and produce products globally in pharma, agrochem and animal health.
Recent group reviews
- Living with our machines: Towards a more sustainable future (2020)
- A tutored discourse on microcontrollers, single board computers and their applications to monitor and control chemical reactions (2020)
- A New World for Chemical Synthesis? (2019)
- Immobilised Reagents and Multistep Processes (2018)
- Engineering Chemistry to Enable Bioactive Small Molecule Discovery (2018)
- Engineering chemistry for the future of organic synthesis (2018)
- Taming Hazardous Chemistry by Continuous Flow Technology (2016)
- Enabling Technologies for the Future of Chemical Synthesis (2016)
- Machine-Assisted Organic Synthesis (2015)
- Flow Chemistry: Intelligent Processing of Gas-Liquid Transformations Using a Tube-in-Tube Reactor (2015)
- Organic Synthesis: March of the Machines (2015)
- Chemistry in a Changing World (2015)
- Flow Chemistry Meets Advanced Functional Materials (2014)
- Camera Enabled Techniques for Organic Synthesis (2013)
- Flow Chemistry Syntheses of Natural Products (2013)
VIDEOS