Dr Éric Śliwiński

Eric graduated from the Université Pierre et Marie Curie UPMC – Paris VI, where he completed a degree in Organic and Bioorganic chemistry under the guidance of Professor Jean François Normant and Doctor Fabrice Chemla. Thereafter, he moved to the University of Leeds and completed his doctoral thesis under the mentorship of Professor Philip J. Kocienski, FRS, on the design and total synthesis of modular anticancer agents. After several assignments in industrial Research and Development, he joined the group of Professor Patrick Couvreur in 2010 at the Institut Galien, Faculté de Pharmacie – Paris Sud, where he was in charge of the design and the synthesis of new terpenoïd-based nanomedicines.

Eric joined the Ley group in March as a postdoctoral research associate on the new EPSRC-funded Critical Mass grant working on novel chemical methods in continuous flow.

Combination of enabling technologies to improve and describe the stereoselectivity of Wolff–Staudinger cascade reaction B. Musio, F. Mariani, E.P. Sliwinski, M.A. Kabeshov, H. Odajima and S.V. Ley, Synthesis201648, 3515-3526

Continuous processing and efficient in situ reaction monitoring of hypervalent iodine(III) mediated cyclopropanation using benchtop NMR spectroscopy B. Ahmed-Omer, E. Sliwinski, J.P. Cerroti and S.V Ley, Org. Process Res. Dev., 201620, 1603-1614

Development of a web-based platform for studying lithiation reactions in silico M.A. Kabeshov, E. Sliwinski, D.E. Fitzpatrick, B. Musio, J.A. Newby, W.D.W. Blaylock, S.V. Ley Chem. Commun201551, 7172-7175

A systems approach towards an intelligent and self-controlling platform for integrated continuous reaction sequences R.J. Ingham,  C. Battilocchio, D.E. Fitzpatrick, E. Sliwinski, J.M. Hawkins, S.V. Ley Angew. Chem. Int. Edn201554, 144-148

Self-assembly of polyisoprenoyl gemcitabine conjugates: influence of supramolecular organization on their biological activity E. Lepeltier, C. Bourgaux, A. Maksimenko, F. Meneau, V. Rosilio, E. Sliwinski, F. Zouhiri, D. Desmaële, P. Couvreur Langmuir, 2014, 30, 6348–6357

A prototype device for evaporation in batch and flow chemical processing B.J. Deadman, C. Battilocchio, E. Sliwinski, S.V. Ley Green Chem. 201315, 2050-2055

Novel isoprenoyl nanoassembled prodrug for paclitaxel delivery S. Mura , F. Zouhiri, S. Lerondel, A. Maksimenko, J. Mougin, C. Gueutin, D. Brambilla, J. Caron, E. Sliwinski, A. Le Pape, D. Desmaele, P. Couvreur Bioconjugate Chem2013, 24, 1840-1849

Polyisoprenoyl gemcitabine conjugates self assemble as nanoparticles, useful for cancer therapy A. Maksimenko, J. Mougin, S. Mura, E. Sliwinski, E. Lepeltier, C. Bourgaux, S. Lepêtre, F. Zouhiri, D. Desmaële, P. Couveur Cancer Letters 2012, In Press.

A synthesis of (aR,7S)-(–)-N-acetylcolchinol and its conjugate with a cyclic RGD peptide G. Besong, D. Billen, I. Dager, P. Kocienski, E. Sliwinski, L.R. Tai, F.T. Boyle Tetrahedron 2008, 64, 4700-4710.

Synthesis of (S)-(–)-N-acetylcolchinol using intramolecular biaryl oxidative coupling G. Besong, K. Jarowicki, P.J. Kocienski, E. Sliwinski, F.T. Boyle Org. Biomol. Chem. 2006, 4, 2193-2207

Carbocyclisation of zinc enolates onto unactivated double bonds: a mechanistic point of view E. Sliwinski, F. Prian, F. Denes, F. Chemla, J-F. Normant Comptes Rendus Chimie 2003, 6, 67-78

Email: es605@cam.ac.uk